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| This monograph is a synthesis of papers
presented at the Prague workshop focusing on novel research
data and new thoughts and approaches on the ecological
relevance of endocrine disruption in wildlife.
The Prague workshop was the last in a
series of meetings organized under the auspices of CREDO
(Cluster for Research on Endocrine Disruption). The themes of
previous workshops were risk assessment and the ecological
relevance of chemically induced endocrine disruption in
wildlife.
All contributors to the workshop are
thanked cordially. Without their enthusiasm and hard work, the
meeting (and this monograph) would not have happened.
Guest Editor
Andreas Kortenkamp
image credit: Joseph Tart/EHP; ShutterStockPurchase This Issue | |
Monograph
Endocrine Disruptors—Exposure Assessment, Novel End
Points, and
Low-Dose and Mixture Effects
Andreas Kortenkamp
p. 7 [ Abstract ] [ Full ] [ PDF ]
Indicators of human and wildlife exposure to endocrine disruptors
Human Exposure to Endocrine-Disrupting Chemicals and Prenatal Risk Factors for Cryptorchidism and Hypospadias: A Nested Case–Control Study
Mariana
F. Fernandez, Begoña Olmos, Alicia Granada, Maria
José López-Espinosa, José-Manuel
Molina-Molina,
Juan Manuel Fernandez, Milagros Cruz,
Fátima Olea-Serrano, and Nicolás Olea
p. 8 [ Abstract ] [ Full ] [ PDF ]
Semen
Quality in Relation to Xenohormone and Dioxin-like Serum Activity
Among Inuits and Three European Populations
Gunnar
Toft, Manhai Long, Tanja Krüger,
Philip S. Hjelmborg, Jens Peter Bonde, Anna Rignell-Hydbom, Ewa
Tyrkiel, Lars Hagmar, Aleksander Giwercman, Marcello
Spanó, Davide Bizzaro, Henning S. Pedersen, Vladymir
Lesovoy, Jan K. Ludwicki, and Eva C. Bonefeld-Jørgensen
p. 15 [ Abstract ] [ Full ] [ PDF ]
Xenoandrogenic
Activity in Serum Differs across European and Inuit Populations
Tanja Krüger, Philip S. Hjelmborg, Bo A.G. Jönsson, Lars
Hagmar, Aleksander Giwercman,
Gian-Carlo Manicardi, Davide
Bizzaro, Marcello Spanò, Anna Rignell-Hydbom, Henning S.
Pedersen, Gunnar Toft, Jens Peter Bonde, and Eva C. Bonefeld-Jørgensen
p. 21 [ Abstract ] [ Full ] [ PDF ]
Fish as Biomonitors of Polybrominated Diphenyl Ethers and
Hexabromocyclododecane
in Czech Aquatic Ecosystems:
Pollution of the Elbe River Basin
Jana
Pulkrabová,
Jana Hajslová,
Jan Poustka, and Radek Kazda
p. 28 [ Abstract ] [ Full ] [ PDF ]
Brominated
Flame Retardants in North-East Atlantic Marine Ecosystems
Munro Jenssen, Eugen G. Sørmo, Kine Bæk, Jenny
Bytingsvik, Hege Gaustad, Anders Ruus, and
Janneche Utne
Skaare
p. 35 [ Abstract ] [ Full ] [ PDF ]
Novel models, end points, and biomarkers
Estrogen
Sensitivity of Target Genes and Expression of Nuclear Receptor
Co-Regulators in Rat Prostate after Pre- and Postnatal
Exposure to the Ultraviolet Filter 4-Methylbenzylidene
Camphor
Stefan Durrer, Colin
Ehnes, Michaela Fuetsch, Kirsten Maerkel, Margret Schlumpf, and
Walter Lichtensteiger
p. 42 [ Abstract ] [ Full ] [ PDF ]
Effects
of Endocrine Disruptors on Dehydroepiandrosterone Sulfotransferase
and Enzymes Involved in PAPS Synthesis:
Genomic and Nongenomic Pathways
Robert Harris, Nahid Turan, Christopher Kirk, David
Ramsden, and Rosemary Waring
p. 51 [ Abstract ] [ Full ] [ PDF ]
In Utero Exposure to
Di(n-butyl)
Phthalate and Testicular Dysgenesis: Comparison
of Fetal
and Adult End Points and Their Dose Sensitivity
I. Kim Mahood, Hayley M. Scott, Richard Brown,
Nina Hallmark, Marion Walker, and Richard M. Sharpe
p. 55 [ Abstract ] [ Full ] [ PDF ]
Effects
of Chronic Genistein Treatment in Mammary Gland, Uterus, and
Vagina
Guillermo
Rimoldi, Julie Christoffel, Dana Seidlova-Wuttke, Hubertus
Jarry, and Wolfgang Wuttke
p. 62 [ Abstract ] [ Full ] [ PDF ]
Endocrine-Disrupting Potential of Bisphenol A, Bisphenol A
Dimethacrylate, 4-n-Nonylphenol, and 4-n-Octylphenol in Vitro:
New Data and a Brief Review
Eva C. Bonefeld-Jørgensen, Manhai
Long, Marlene V. Hofmeister, and Anne Marie Vinggaard
p. 69 [ Abstract ] [ Full ] [ PDF ]
Endocrine
Disruptors and the Thyroid Gland—A Combined in Vitro and in Vivo
Analysis
of Potential New Biomarkers
Cornelia
Schmutzler, Inka Gotthardt, Peter J. Hofmann, Branislav Radovic,
Gabor Kovacs, Luise Stemmler, Inga Nobis, Anja Bacinski, Birgit
Mentrup,
Petra Ambrugger, Annette Grüters, Ludwik K.
Malendowicz, Julie Christoffel, Hubertus Jarry,
Dana
Seidlovà-Wuttke, Wolfgang Wuttke, and Josef Köhrle
p. 77 [ Abstract ] [ Full ] [ PDF ]
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Low-dose effects of endocrine disruptors
Statistical
Power Considerations Show the Endocrine Disruptor Low-Dose Issue
in a New Light
Martin
Scholze and Andreas Kortenkamp
p. 84 [ Abstract ] [ Full ] [ PDF ]
Activity
of Xenoestrogens at Nanomolar Concentrations in the E-Screen
Assay
Elisabete
Silva, Martin Scholze, and Andreas Kortenkamp
p. 91 [ Abstract ] [ Full ] [ PDF ]
Mixture effects of endocrine disruptors and their assessment
Ten
Years of Mixing Cocktails: A Review of Combination Effects of
Endocrine-Disrupting Chemicals
Andreas Kortenkamp
p. 98 [ Abstract ] [ Full ] [ PDF ]
Low-Level
Exposure to Multiple Chemicals: Reason for Human Health Concerns?
Andreas
Kortenkamp, Michael Faust, Martin Scholze, and Thomas Backhaus
p. 106 [ Abstract ] [ Full ] [ PDF ]
Mixtures
of Estrogenic Chemicals Enhance Vitellogenic Response in Sea Bass
Ana D. Correia, Sandro Freitas, Martin
Scholze, José F.Gonçalves, Petra Booij, Marja H.
Lamoree,
Evaristo Mañanós, and Maria A. Reis-Henriques
p. 115 [ Abstract ] [ Full ] [ PDF ]
Combined
Exposure to Anti-Androgens Exacerbates Disruption of Sexual Differentiation
in the Rat
Ulla Hass, Martin Scholze, Sofie Christiansen, Majken
Dalgaard, Anne Marie Vinggaard, Marta Axelstad , Stine Broeng
Metzdorff, and Andreas Kortenkamp
p. 122 [ Abstract ] [ Full ] [ PDF ]
Enhanced
Micronucleus Formation and Modulation of Bcl-2:Bax in MCF-7 Cells
after Exposure to Binary Mixtures
Rebecca Hewitt, Albert Forero, Paz J. Luncsford,
and Francis L. Martin
p. 129 [ Abstract ] [ Full ] [ PDF ]
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